Развитие ХСО и предшествующей пневмонией.

Цель: Изучить связь между развитием ХСО и предшествующей пневмонией.
Дизайн: Национальное когортное исследование.

Методы: Данные получались путем анализа национального фонда страховых выплат Кореи за период с 2002 по 2015 годы. Были сформированы группа пациентов с ХСО (n=23,436) и соответсвующая по возрасту, полу, доходу и региону проживания контрольная группа (n=93,744) в соотношении 1:4.

Результаты:.
The crude and adjusted odds ratios (ORs) of pneumonia occurring before the index date for COM were analyzed using a conditional logistic regression model. Additionally, ORs of the number of diagnoses of pneumonia (≥5 times vs. <5 times) for COM were analyzed.

Results: The incidence of pneumonia (9.3%) was significantly higher (p<0.001) in the COM group than in the control group (7.2%). The ORs of pneumonia were significantly higher in the COM group than in the control group. Pneumonia (adjusted OR=1.31, 95% confidence interval [CI]=1.25–1.38, p<0.001) increased the ORs for COM in all ages and gender. Pneumonia being diagnosed ≥5 times before the index date showed higher ORs (adjusted OR=1.34, 95% CI=1.20–1.49, p<0.001) for COM than pneumonia being diagnosed <5 times.

Conclusions: Our population-based nationwide cohort study indicates that diagnosis of pneumonia was significantly associated with an increased incidence of COM.